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Moisturizing & Barrier

Phytosphingosine

winter-lipid-balance
BarrierMoisturizing
INCI: Phytosphingosine
In short · TL;DR
Category
Moisturizing & Barrier
Effect
Ceramide precursor, barrier reconstruction, antimicrobial
Concentration
0.05-0.5%
Effect
Ceramide precursor, barrier reconstruction, antimicrobial
Mechanism
Substrate for ceramide synthesis, repairs lamellae, PPARα activation
Typical concentration
0.05-0.5%
Onset
8 weeks for TEWL reduction
Cautions
Precipitates at high pH
Evidence & references
Cosmetics & Toiletries 2003
Journal

Related Journal

5
Skin Longevity SeriesThe Invisible Dryness Under Air Conditioning — The Science of TEWL and Barrier FunctionSkin Longevity SeriesThe Season-Change Switch: How the Autonomic Nervous System and the Skin Barrier Move TogetherSkin Longevity SeriesCeramide, the Protagonist — The Science of the Lipid That Binds the SkinSkin Longevity SeriesDesigning Moisture in Layers — Humectant, Occlusive, EmollientSkin Longevity SeriesLipid Balance in Deep Winter: Designing Skin's Oils from Inside and Out
This page is reference information and does not guarantee efficacy. Figures vary by test conditions (in vitro / manufacturer / concentration). It does not indicate pharmaceutical efficacy.
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