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Moisturizing
Panthenol
MoisturizingSoothingBarrier
INCI: Panthenol
In short · TL;DR
Category
Moisturizing
Effect
Helps the stratum corneum retain water, keeping skin healthy and moist
Concentration
Japanese quasi-drug precedent (D-panthenol): 0.1–0.3% in lotion, cream and packs (MHLW list). A 0.5–5% range in cosmetics is not confirmed by primary sources (CIR 2022 concluded it is safe at current use concentrations).
Effect
Helps the stratum corneum retain water, keeping skin healthy and moist
Mechanism
A precursor converted to pantothenic acid in the body. In addition to hygroscopic water retention, research suggests it contributes to stratum corneum conditioning and prevention of rough skin
Typical concentration
Japanese quasi-drug precedent (D-panthenol): 0.1–0.3% in lotion, cream and packs (MHLW list). A 0.5–5% range in cosmetics is not confirmed by primary sources (CIR 2022 concluded it is safe at current use concentrations).
Onset
The moisturizing feel is immediate; improvement in the feel of rough skin comes with continued use
Cautions
Basically low-irritation. Rarely, a hypersensitivity reaction
Evidence & references
MHLW active-ingredient list / CIR 2022 https://pubmed.ncbi.nlm.nih.gov/36177798/ (checked 2026-10-20)
This page is reference information and does not guarantee efficacy. Figures vary by test conditions (in vitro / manufacturer / concentration). It does not indicate pharmaceutical efficacy.
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