HOME ／ Ingredients ／ Antioxidant
Antioxidant

Bakuchiol

SoothingAntioxidantFirmness / Aging
INCI: Bakuchiol
In short · TL;DR
Category
Antioxidant
Effect
In a study applying 0.5% cream twice daily for 12 weeks (44 people), wrinkle area and hyperpigmentation decreased, with no statistical difference from 0.5% retinol (once daily).
Concentration
0.5-2%
Effect
In a study applying 0.5% cream twice daily for 12 weeks (44 people), wrinkle area and hyperpigmentation decreased, with no statistical difference from 0.5% retinol (once daily).
Mechanism
Plant-derived (Psoralea corylifolia seed) meroterpene. Partial agonist activity at retinoic acid receptors (RAR). Promotes collagen I/III/IV gene expression. Also possesses antioxidant and anti-inflammatory activity
Typical concentration
0.5-2%
Onset
Wrinkle improvement and pigmentation improvement: 12 weeks
Cautions
No human studies on safety during pregnancy or breastfeeding were found; consult a doctor before use. In the study, scaling and stinging were reported more often with retinol.
Evidence & references
Dhaliwal 2019 https://pubmed.ncbi.nlm.nih.gov/29947134/ (44 people, 12 weeks, twice daily) (checked 2026-10-20)
Journal

Related Journal

7
Aesthetic Medicine vs Home CareRetinol formulations vs prescription tretinoin -- the science of concentration and efficacySkin Longevity SeriesChoosing Skin Longevity: The Pledge KAIAN Makes This JulySkin Longevity SeriesThe 4-Week Summer Damage Recovery BlueprintSkin Longevity SeriesThe First Three Signs of Aging — Preventive Skincare from Your 30sSkin Longevity SeriesThe Three Dermal Pillars — Collagen, Elastin and Hyaluronic AcidSkin Longevity SeriesRetinol vs Bakuchiol: Is the "Natural Retinol" Claim Real?Skin Longevity SeriesA Century of Beauty Research
This page is reference information and does not guarantee efficacy. Figures vary by test conditions (in vitro / manufacturer / concentration). It does not indicate pharmaceutical efficacy.
← Back to Ingredients