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Antioxidant

Bakuchiol

2026-trend-roundup
AntioxidantFirmness / AgingSoothing
INCI: Bakuchiol
In short · TL;DR
Category
Antioxidant
Effect
Retinol-like wrinkle improvement and collagen synthesis promotion without irritation. Also called 'next-generation retinol'
Concentration
0.5-2%
Effect
Retinol-like wrinkle improvement and collagen synthesis promotion without irritation. Also called 'next-generation retinol'
Mechanism
Plant-derived (Psoralea corylifolia seed) meroterpene. Partial agonist activity at retinoic acid receptors (RAR). Promotes collagen I/III/IV gene expression. Also possesses antioxidant and anti-inflammatory activity
Typical concentration
0.5-2%
Onset
Wrinkle improvement and pigmentation improvement: 12 weeks
Cautions
Safe for use during pregnancy (no contraindication unlike retinol). Can be used during the day. Additive effect when combined with retinol
Evidence & references
Dhaliwal et al. (2019) 'Prospective randomized double-blind assessment of bakuchiol vs retinol' PubMed (equivalent effect to retinol 0.5%, significantly less irritation)
Journal

Related Journal

10
Aesthetic Medicine vs Home CareRetinol formulations vs prescription tretinoin -- the science of concentration and efficacySkin Longevity SeriesChoosing Skin Longevity: The Pledge KAIAN Makes This JulySkin Longevity SeriesThe 4-Week Summer Damage Recovery BlueprintSkin Longevity SeriesThe First Three Signs of Aging — Preventive Skincare from Your 30sSkin Longevity SeriesThe Three Dermal Pillars — Collagen, Elastin and Hyaluronic AcidSkin Longevity SeriesRetinol vs Bakuchiol: Is the "Natural Retinol" Claim Real?Skin Longevity SeriesA Century of Beauty ResearchSkin Longevity SeriesTrend Check: The Real Power of Exosome CosmeticsSkin Longevity SeriesGifting "Functional Longevity" This Christmas — Choosing Skincare as a Scientific GiftSkin Longevity Series[Trend Check] The 2026 Buzz-Ingredient Reckoning
This page is reference information and does not guarantee efficacy. Figures vary by test conditions (in vitro / manufacturer / concentration). It does not indicate pharmaceutical efficacy.
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