Sebum Care

Zinc PCA

Sebum / AcneMoisturizing

INCI: Zinc PCA

In short · TL;DR

Category

Sebum Care

Effect

The zinc salt of PCA (a component of natural moisturising factor). Used to moisturise and to help prevent shine from sebum.

Concentration

Primary data on a use level are unconfirmed.

Effect

The zinc salt of PCA (a component of natural moisturising factor). Used to moisturise and to help prevent shine from sebum.

Mechanism

The mechanism on sebum is not confirmed by primary data on the single ingredient; human reports are limited to multi-ingredient formulas containing zinc PCA.

Typical concentration

Primary data on a use level are unconfirmed.

Onset

A change in feel over several days to several weeks.

Cautions

Zinc can precipitate at high pH, so formulation pH management is required.

Evidence & references

https://pubmed.ncbi.nlm.nih.gov/32574015/ / https://pubmed.ncbi.nlm.nih.gov/39778065/ (both multi-ingredient formulas) (checked 2026-10-20)

This page is reference information and does not guarantee efficacy. Figures vary by test conditions (in vitro / manufacturer / concentration). It does not indicate pharmaceutical efficacy.

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