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Tripeptide-1 (GHK)

beauty-research-century
Firmness / Aging
INCI: Tripeptide-1
In short · TL;DR
Category
Peptides
Effect
GHK without copper, gene expression modulation, wound healing
Concentration
Stock 1-5%, pure 0.01-0.1%
Effect
GHK without copper, gene expression modulation, wound healing
Mechanism
Shifts the expression of ~4,000 genes toward a youthful state (in vitro DNA microarray in human fibroblasts, Pickart et al.). Note: efficacy of copper-free GHK applied topically relies substantially on GHK-Cu findings; standalone clinical evidence is relatively limited.
Typical concentration
Stock 1-5%, pure 0.01-0.1%
Onset
12 weeks for comprehensive skin regeneration
Cautions
Synergistic with copper variant
Evidence & references
Pickart et al., Biomed. Res. Int. 2012
Journal

Related Journal

2
Skin Longevity SeriesThe First Three Signs of Aging — Preventive Skincare from Your 30sSkin Longevity SeriesA Century of Beauty Research
This page is reference information and does not guarantee efficacy. Figures vary by test conditions (in vitro / manufacturer / concentration). It does not indicate pharmaceutical efficacy.
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