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Antioxidant

Spermidine

2027-manifesto
Antioxidant
INCI: Spermidine HCl
In short · TL;DR
Category
Antioxidant
Effect
Autophagy inducer, mitochondrial biogenesis, longevity signaling
Concentration
0.01-0.1%
Effect
Autophagy inducer, mitochondrial biogenesis, longevity signaling
Mechanism
eIF5A activation → autophagy gene expression → clearance of aged cellular proteins
Typical concentration
0.01-0.1%
Onset
8-12 weeks for wrinkle/sagging trend
Cautions
Heat sensitive
Evidence & references
Nat. Med. 2016: longevity extension, human cohort
Journal

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This page is reference information and does not guarantee efficacy. Figures vary by test conditions (in vitro / manufacturer / concentration). It does not indicate pharmaceutical efficacy.
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