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Dimethicone

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MoisturizingBarrier
INCI: Dimethicone
In short · TL;DR
Category
Oils & Lipids
Effect
A silicone emollient that forms a silky protective film and suppresses moisture evaporation.
Concentration
Loading-dependent (from a few percent).
Effect
A silicone emollient that forms a silky protective film and suppresses moisture evaporation.
Mechanism
Polydimethylsiloxane forms a breathable film on the stratum corneum surface, suppressing TEWL while giving a smooth feel.
Typical concentration
Loading-dependent (from a few percent).
Onset
Feel and protective effect immediately after application.
Cautions
Few significant cautions.
Evidence & references
参考文献: Final report on the safety assessment of stearoxy dimethicone, dimethicone, methicone, amino bispropyl dimethicone, aminopropyl dimethicone, amodimethicone, amodimethicone hydroxystearate, behenoxy dimethicone, C24-28 alkyl methicone, C30-45 alkyl methicone, C30-45 alkyl dimethicone, cetearyl methicone, cetyl dimethicone, dimethoxysilyl ethylenediaminopropyl dimethicone, hexyl methicone, hydroxypropyldimethicone, stearamidopropyl dimethicone, stearyl dimethicone, stearyl methicone, and vinyldimethicone(PubMed PMID:14555417 https://pubmed.ncbi.nlm.nih.gov/14555417/
Journal

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This page is reference information and does not guarantee efficacy. Figures vary by test conditions (in vitro / manufacturer / concentration). It does not indicate pharmaceutical efficacy.
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